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Antibody library

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Overview

The diversity of a human individual antibody repertoire is estimated to as high as 1011 - 1013 which is made by rearrangement of six antibody complementary determine regions (CDRs). Recently, the synthetic antibody libraries by directly CDRs design is used to rapidly discovery more powerful and comprehensive antibodies. Since the fast evolved of low cost and high capacity of array-based oligo pools, synthetic antibody library construction by array-based oligo pools is widely used and show promising result in clinical.

Dynegene technology now provide 230 bps DNA oligo pools synthesis with low error rate ( ~ 0.1% bps) and the cost is about 10% of conventional DNA oligo synthesis. In addition, Dynegene technology provide service of constructing oligo pools into phage-displayed, yeast displayed, as well as mammalian displayed plasmid. Service of biopanning through phage-displayed libraries is also provided by us. All of this is to help pharmaceutics companies to rapidly evolve to provide more solution in combating diseases. Please contact us for more detail.

 

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Dynegene Next-Gen Synthesis: Powering Biotech Revolution With Nucleic Acids

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Address: Floor 2, Building 5, No. 248 Guanghua Road, Minhang District, Shanghai

Email: zhengyuqing@dynegene.com

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