Overview

Targeted sequencing technology enables probe design for specific genomic regions. Leveraging its core advantages ofhigh throughput, high flexibility, and cost-effectiveness,it has become an indispensable key technology in modern molecular breeding. While significantly shortening the breeding cycles and reducing costs, it also provides powerful tools for cutting-edge breeding strategies such as tackling complex genomes and achieving polygenic trait stacking. It has been widely applied in germplasm identification, superior trait screening, germplasm genetic relationship analysis, population genetics analysis, and molecular marker development.

Leveraging our proprietary high-throughput DNA synthesis platform,DNAdynegene offers a full-service solution for customized liquid-phase hybridization capture probes tailored to crop, livestock, and aquaculture breeding scenarios. Our integrated solution covers probe design, synthesis, and modification to supporting capture reagents, boosting molecular breeding toward higher efficiency, lower cost and greater customization.

Targeted Capture Workflow

Dynegene’s Targeted Sequencing Solutions

Key Technical Workflow

Enzymatic Fragmentation Library Preparation

• Compatible with a wide range of input amounts and multiple sample types
• Easy operation: fragmentation and end repair in a single tube reaction
• Compatible with Illumina and MGI sequencing platforms

Liquid-Phase Hybridization Capture System

• Provides high-performance DNA hybridization capture systems
• Enables multiplex hybridization to reduce cost
• Compatible with Illumina and MGI sequencing platforms

Capture Performance Data

Superior Capture Efficiency

The figure shows the capture performance across different species, with sequencing performed using Dynegene’s hybridization capture reagents.

Ordering Information

Library Preparation

Hybridization Capture

Custom Probes

For ordering, please contact us.