Human mitochondrial DNA (mtDNA) is 16,569 bp in length and contains a total of 37 genes. Due to its compact gene arrangement and being a naked DNA molecule, it is highly susceptible to damage, leading to mutations. Furthermore, the lack of effective DNA damage repair mechanisms results in a higher mutation rate in mtDNA compared to the nuclear genome.mtDNA mutations can cause various mitochondrial diseases, and mtDNA also serves as a key target in molecular evolutionary research.Using double-stranded RNA probe technology, Dynegene offers a complete human mitochondrial targeted enrichment solution, enabling comprehensive detection of the entire human mitochondrial genome.